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Despite modern reconstruction techniques and replantation, the preservation of a severely traumatised lower limb or a limb that is affected by painful chronic osteomyelitis usually yields poorer functional results than amputation and prosthetic use [2].
As expected, extraarticular stabilization with MSTC yields better functional results, especially in sub-terms of pain, ROM and ADL, revealed by the Constant Scoring system.
Open reduction with lag screws did not yield better functional results than closed reduction with transversally inserted K-wires in extra-articular fractures of the proximal phalanx.
Biological reconstruction, using distraction osteogenesis or frozen autografts, could yield good functional results and QOL without leading to an increase in the incidence of local recurrence [ 28].
Intramedullary nailing of acute two- and three-part proximal humerus fractures yields satisfactory clinical and functional results.
Though the saddle prosthesis was proposed as advance in tumor-related pelvic surgery, the present study indicates that it yields unsatisfactory clinical and functional results due to both clinical complications and the poor biomechanics of the device.
Semitendinosus and gracilis tendons have both been used for the reconstruction of large defects caused by chronic Achilles tendon ruptures and have yielded good clinical and functional results [ 19– 22].
In this situation a nonconstrained shoulder prosthesis yields a limited functional result or may even be contraindicated.
Valid functional results.
Functional results were excellent.
Tyr200 faces away from the ligand, yet was very sensitive to substitution: the only mutation that yielded functional receptors was Y200F, which resulted in an ∼100-fold increase in EC50, similar to data previously reported.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com