Sentence examples for yielded response rates of from inspiring English sources

Capecitabine, an orally administered 5-FU prodrug, yielded response rates of 11% in patients with advanced HCC [ 15].

In MBC, single-agent gemcitabine has yielded response rates of up to 37% in chemonaive patients, [ 14- 16] and 26% in those pretreated with anthracyclines [ 16- 18].

Irinotecan administered on a weekly schedule yielded response rates of >20%% and iniparib had shown a PFS/OS advantage in advanced TNBC when combined with DNA-damaging chemotherapeutics in the phase II setting [ 7, 32].

Analyses based on the per-protocol sample yielded response rates of 43% (6 out of 14 participants) in the MBCT group and 7% (1 out of 14) in the TAU group.

Whereas studies by Bernatsky and colleagues [ 12] and Glazier and colleagues [ 13] yielded response rates of 31%and68%8%, respectively, our study produced a response rate of only 25%.

Studies involving anthracyclines, ifosfamide, taxanes, camptothecins, and platinum analogs have all yielded response rates of less than 10% with no demonstrable improvement in overall survival (Shore et al. 2003).

Anthracyclines such as doxorubicin and epirubicin can yield response rates of around 20%to40%0% in MBC patients when used as single agents, and up to 60% when given as part of combination regimens [ 2].

Single-agent paclitaxel has shown an initial 17% activity in advanced cervical cancer at a dose of 170 mg m−2 in 24-h infusion (Thigpen et al, 1995; McGuire et al, 1996), whereas subsequent doses of 250 mg m−2 over 3 h with granulocyte-colony stimulating factor (G-CSF) support yielded response rates (RRs) of 25% (Kudelka et al, 1997).

In psoriasis vulgaris trials, the emerging IL-17 antagonists yielded response rates that reflect virtual elimination of disease (45, 46).

TMZ has been approved for the treatment of brain metastasis and has demonstrated clinical activity against melanoma, but overall it yields response rates similar to that of DTIC.

The detection of V600E BRAF mutations has fundamental clinical consequences as the treatment option with BRAF inhibitors such as vemurafenib or dabrafenib yields response rates of ∼48%.