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This study has some limits which need to be addressed: LDQ has not yet been validated for the analgesics dependence and thus further validity studies are required.
Day-case laparoscopic cholecystectomy has not yet been validated for acute cholecystitis.
Magnetic resonance imaging (MRI) provides three-dimensional noninvasive quantitative methods of cerebral blood flow (CBF) imaging, but these MRI techniques have not yet been validated for mice.
Specific binding sites have not yet been validated for most ScPma1p inhibitors, including DMM-11 [24]; ebselen [25]; the natural products chebulagic acid and tellimagrandin II [26]; and the inhibitors found in a recent high-throughput screen [27].
The high positive serology result has to be assessed with caution as the rapid test has not yet been validated for African wildlife species [22], [37].
Although we selected miRNAs that are thought to target IRS-1 3'UTR, most of them have not yet been validated for whether they actually repress IRS-1 expression.
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A dizziness specific acceptance scale is under construction, (Kirby S, 2014, personal communication) but has not yet been validated and so for the present trial we will use the revised version of the Acceptance and Action Questionnaire-II (AAQ-II).
An exception is the Mom's Support Circle (Additional File 1) measure, which was devised specifically for the NICU study and has not yet been validated (See Table 1 for power analyses).
At present, AD biomarkers have not yet been validated as surrogate endpoints for regulatory purposes and therefore cannot be used as the primary indicators of efficacy.
First, since Ciona is located in an area of the phylogenetic tree for which miRNAs have not yet been validated, we chose to search for potential miRNA sequences across widely divergent phyla and subphyla.
To date, no biomarker has yet been validated as a consensual endpoint for MTA phase 1 trials.
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however been validated for
already been validated for
yet been identified for
yet been replicated for
yet been released for
yet been indicted for
yet been tested for
yet been assigned for
yet been declared for
yet been set for
yet been approved for
yet been finalized for
yet been accepted for
yet been scheduled for
yet been designated for
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