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"We've developed a new approach that will allow us to identify genes that haven't yet been implicated in touch and pain," she said.
To the extent that BER genes have yet been implicated in glioblastoma oncogenesis, the framework constitutes a form of "non-oncogene" addiction.
Similarly strong effects were observed for the Hmx2, Hmx3, and Otp homeobox genes that have not yet been implicated in the neural tube GRN.
MicroRNAs (miRNAs), however, represent a class of molecules that until recently had not yet been implicated in executing β4-mediated function.
SURFINs have not yet been implicated in anchoring surface antigens to the erythrocyte cytoskeleton, but we think that this is a plausible hypothesis that should be tested experimentally.
Although the ADAMTS family has not yet been implicated in this disorder, numerous studies have identified a role for metalloproteinases (MMPs) in SpA susceptibility and severity [ 22– 22].
Similar(41)
To our knowledge, Wnt/β-catenin has as yet not been implicated in muscle hypertrophy in vivo.
Multiple signaling components such as MAP kinases [36], [37], IBR5 protein phosphatase [38], [39], phospholipase A2 [41], [41] and RAC GTPases [42], [43] have been reported to be involved in auxin signaling yet have not been implicated in the short auxin signaling SCFTIR1 pathway.
SDF-1/CXCL12 is a unique CXC chemokine as it exerts mainly a homeostatic function, yet it has been implicated in inflammation such as in RA [ 13, 14, 17, 29].
Furthermore, there are no reports of biofilm production by Kocuria in the literature, yet it has been implicated in device-related bacteremia, implying that the colonization of Kocuria on a device will likely result in chronic recurrent bacteremia in a compromised host.
Additionally, these analyses also provide insight into the cross-talk between innate immunity pathways and other biological processes, such as adaptive immunity, cancer and diabetes, and intriguingly, suggests links to other pathways, which as yet, have not been implicated in the innate immune response.
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