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Production of recombinant proteins by yeast plays a vital role in the biopharmaceutical industry.
The core autophagy machinery comprising 18 autophagy-related (Atg) proteins in yeast plays an essential role in autophagosome formation; however, the molecular role of each Atg factor and the mechanism of autophagosome formation remain elusive.
The evolutionarily conserved MAPK Sty1 and bZIP transcription factor Atf1 in fission yeast play a major role in response to various environmental stress factors [9], [26].
Taken together, these results indicate that dietary yeast plays a much larger role in modifying the response to exercise-training than does dietary sugar.
Vam7p in yeast plays its role in vacuole formation and assembly, while the Vam7-like protein Yup1 of U. maydis is reported to be critical for endocytosis [3].
Rad52 is the central HR protein in budding yeast, playing a demonstrated role in almost all Rad51-dependent and –independent HR [3], [4], [5], [66].
It has previously been reported that dietary yeast plays a critical role in DR responses and that survival of normoxic flies is largely insensitive to changes in dietary sucrose [19], [20].
Indeed, Crt1/RFX in the budding yeast plays a role in DNA damage response [ 34].
DOI: http://dx.doi.org/10.7554/eLife.08208.001 Microbes like bacteria and yeast play important roles in the environment, human health and even some industrial processes.
The urea cycle operates in terrestrial animals to detoxify ammonia, and in yeast plays a principal role in the biosynthesis of arginine.
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