An extensive search of the bibliography from recent years was performed using PubMed and the Cochrane database.
The analysis of trends over years was performed using Chi-square test for trend for categorical variables and Spearman's correlation coefficient test for continuous variables.
A multidirectional statistical analysis of the OCC trends over the past 25 years was performed using the databases of the Hong Kong Cancer Registry.
Comparisons of biochemical values before and after 1 year were performed using the Wilcoxon signed-rank test.
Given serum cotinine values have been shown to follow a log-normal distribution, [ 6] regression models for each survey year were performed using the log of serum cotinine as the dependent variable.
One hundred and forty-six examinations in 73 patients (mean age 53 ± 12 years, 58 men) were performed using a 1.5 Tesla system and compared to EMB.
The 5-year RSA examinations were performed using a digital radiography system consisting of 2 ceiling-mounted X-ray sources (RAD-92; Varian Medical Systems, Palo Alto, CA) and corresponding digital detectors (Canon CXDI-55C; Canon USA, Lake Success, NY).
The comparisons between groups of < 5 years and ≥ 5 years of clinical cure were performed using the Mann–Whitney U-test for non-parametric values.
Next we carried out an analysis by cohort size (<35,000, >35,000) and finally by definition of sub-fertility used: (a) BI versus IPI and (b) categorical measures (e.g. <1 year, >3 years) vs. continuous measures Analyses were performed using Review Manager version 5.1 software [ 28].
