Excess Hazards Ratios (EHR) at five years were computed using a generalised linear model with a Poisson error structure [ 24].
Estimates of OS at 2 and 5 years were computed using the Kaplan Meier method, a log-rank test was used to analyze the effect of CI and PET/CT results on OS.
To determine the association of waiting times with mortality, excess hazards ratios (EHRs) at 5 years were computed using a generalised linear model with a Poisson error structure (Dickman et al, 2004).
Expected survival years were computed using the same procedure, but substituting the observed PDC value with that expected in the given scenario, keeping the values of all other covariates unchanged.
Healthcare costs were based on costs-of-illness studies in the Netherlands, 19 20 and the healthcare outcome measure 'quality-adjusted life year (QALY)' was computed using the Global and Dutch burden of disease studies.
In this experiment, the 31-year mean monthly climatological SST was computed using OISST, and then applied to the same 31-year time period as the CTL simulations (hereinafter referred to as the CLM runs).
In this study, a water balance was computed using 10 years of data collected at the Upper Sheep Creek Watershed, a 26-ha semi-arid mountainous sub-basin within the Reynolds Creek Experimental Watershed in southwest Idaho, USA.
95% CI was computed using t-distribution.
bExpected heterozygosity was computed using Nei (1987).
AUC was computed using the trapezoidal rule.
