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Patients aged <50 years had better results at the end of 1 <span class="lh">year when treated with external fixation.
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A similar result was reported for patients with early axial SpA with a symptom duration of less than 3 years when treated with infliximab [ 44].
with a vaccine against grass pollen became tolerized after 3 injections over 8 weeks compared to 54 injections over 3 years when treated with subcutaneous immunization (52).
Inspection of hazard ratios showed that ACT-responders are at a 3.1-fold (unadjusted for clinical covariates) or 4.4-fold (adjusted) lower risk of death within 5-years, when treated with ACT.
Evidence for this comes from recent adjuvant therapy trials in which those patients who had R0 or R1 resections still had mortality rates of ~90% at 5 years when treated with surgery alone (ESPAC-1 and CONKO-001).
Evaluation of outcome according to chemotherapy regimen and age found that there were no differences in PFS and OS between age groups when treated with bevacizumab plus fluoropyrimidine monotherapy, but both PFS and OS were longer in patients aged <70 vs. ≥70 years and <75 vs. ≥75 <span class="lh lhl">years when treated with bevacizumab plus doublet combination chemotherapy.
Non-small-cell lung cancer (NSCLC) accounts for almost 80% of lung cancer and the median survival of metastatic NSCLC is only around 1 year, even when treated with platinum chemotherapy.
A predictive value for nuclear cyclin D1a was demonstrated for colon cancer, as patients with high expression of this protein showed longer 5-year RFS and 5-year CSS when treated with 5-FU/LEV, compared to surgery only.
It was also reported that patients with both HER2 and p53 positive tumors had an improved 10-year survival when treated with a high dose FAC (fluorouracil, doxorubicin, cyclophosphamide) regimen [ 29].
A large proportion of ER+ LN- patients are disease-free more than 10 years after diagnosis when treated with endocrine therapy alone and, therefore, could forgo chemotherapy and the associated toxicities.
In VKA-naïve patients, 1.5 % per year experienced the primary outcome when treated with apixaban compared with 1.8 % per year of patients treated with warfarin.
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CEO of Professional Science Editing for Scientists @ prosciediting.com