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Controls (pPROM without cerclage) were matched 2.5:1 by year of presentation.
Controls were matched to cases by age (±2 years), gender, and year of presentation.
However, the year of presentation to hospital for each patient was used as a surrogate indicator to estimate the different circulating dengue serotypes in each epidemic year.
However, patient-specific dengue serotype data for each subject was unavailable; thus the year of presentation was used as a surrogate index to estimate dominant circulating serotype in each epidemic year.
In order to build the model, a forward stepwise variable selection approach was used to add the a priori defined clinically important variables including age, gender, ethnicity, CCI, DCSI, nephropathy, serum creatinine >2.0 mg/dL, HbA1c, year of presentation and variables with P < 0.20 between the metformin non-users and users.
The risk reduction was 40% (aRR = 0.60, 95% CI: 0.37 0.98, P = 0.04) after controlling for age, gender, ethnicity, CCI, DCSI, nephropathy, hyperlipidemia, serum creatinine >2.0 mg/dL, HbA1c and concurrent medications including statins, ACEI, sulfonylurea and insulin, and year of presentation (Table 2).
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Of these studies, 117 (47%) were published in a peer reviewed journal within 5 years of presentation.
Inclusion criteria included free papers presented at the 2008 and 2010 ESSKA congresses, as these years would allow for evaluation of all corresponding papers published within five years of presentation.
Patients with phenotypic extremes in survival were selected: good prognosis (event-free survival for at least 5 years; n=25) and poor prognosis (events [death, requirement for left ventricular assist device, or cardiac transplant] within the first 2 years of presentation with HF symptoms; n=18).
In its first two years of presentation, "The Artist" and "Argo" were in their respective years very sadly the only nominated live action features filmed in Hollywood.
Despite this, the majority of patients need long term renal replacement therapy within 2 years of presentation (Noris et al, 2010).
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