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If these signals go wrong, disease is the consequence.
This turned out to be a misdiagnosis, and at the trial Wei argued that treatment for the wrong disease worsened Li's condition.
Because diagnosing the disease is a process of elimination, and the symptoms mimic those of other neurological disorders, patients are also at risk being diagnosed and treated for the wrong disease.
How are such predictions made, and how can they go wrong?Disease predictions come from mathematical models that group the population at risk of a disease into categories and describe how people move between them.
The determination of human mitochondrial DNA (mtDNA) haplogroups is not only crucial in anthropological and forensic studies, but is also helpful in the medical field to prevent establishment of wrong disease associations.
"Your husband caught the wrong disease," the attorney told us, shortly before we left.
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The sequencing of the genome is a landmark of progress in specifying information, decoding it into its many coded meanings and learning how it goes wrong in disease.
He said that mapping the DNA in the so-called epigenome and the ways that it coordinates the body's biological activities would help scientists "understand the process that generates a human being — and what goes wrong in disease".
"NCATS is a unique new entity, purpose-built to solve this central paradox: that we know more than ever before about how the body works and what goes wrong in disease but lack the equivalent ability to fix it," said NCATS director Chris Austin.
A continuing stream of advances in the neurosciences has dramatically altered long-held beliefs about how the brain works and what goes wrong in disease.
These RNAs act to promote or repress cell proliferation, differentiation and death, homeostasis, and migration during development, all processes that go wrong in disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com