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The animals were randomly divided into incision and burn wound groups with each group having 56 animals.
Male Sprague Dawley rats weighing 250 300 g were randomly divided into incision and burn wound groups.
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The closed wound group of patients showed significantly shortest wound healing time, followed by the limited excision group of patients; the wide excision group of patients showed the longest healing time.
Results: The limited excision group of patients had a highly significant shorter operative time than the closed wound group of patients (p<0.001).
Apart from the minimal non-significant elevation of the rate of recurrence in the closed wound group of patients, there was no difference between the three groups.
Group 2: diabetic wound group with implanted fibrin gel (DM).
Group 3: diabetic wound group with implanted fibrin gel and 1 × 10 MSCs (DM + MSCs).
Group 4: diabetic wound group with implanted fibrin gel and 1 × 10 EPCs (DM + EPCs).
Each time point had 3 mice for either skin or tongue wound group.
Group 5: diabetic wound group with implanted fibrin gel and combined 0.5×1010 EPCs and 0.5 × 10 MSCs (DM + EPCs + MSCs).
However, those in the other lower-extremity wound group could not have the codes listed for diabetic foot ulcers but could have the exclusionary codes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com