As long as the underlying wound exists, WOWH mechanism will respond to it until the wound healing power is exhausted.
There is no system in nature to stop or reverse the wound healing process in the middle stage when the wound exists.
Its agonised dilemmas and wounds exist only to be resolved within a couple of hours.
It's hard to admit, but wherever a relationship exists, the possibility of someone getting wounded exists.
Thus, most chronic infections, including bacterial that are associated with chronic wounds, exist as biofilm communities [13], [15] [17].
Blocking one or two elements of the networks may delay the signal flows for a while but cannot block them completely, as long as wounds exist.
It has been speculated for several years that bacteria that colonize chronic wounds exist as biofilm communities (Serralta et al. 2001, Percival and Bowler 2004).
This study revealed that those patients with a diabetic neuropathic foot ulcer that healed within 20 weeks using standard care were more likely to have a smaller wound that existed for a shorter period and to be non-whites, compared with patients whose wounds did not heal within 20 weeks.
While electrospun materials have been frequently used in tissue engineering no wound dressings exist that significantly improved wound healing effectively.
While evidence-based recommendations for wound care exist, many practitioners continue to treat wounds based on personal preference some employing unnecessary or possibly detrimental techniques [21].
