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Finally, we asked if loss of Pml would surrogate for Tsc2 LOH, which invariably occurs in human TSC tumours and kidney tumours from Tsc2+/− mice (Green et al, 1994; Henske et al, 1996; Onda et al, 1999).
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It was hypothesized that serum LRG would potentially surrogate for CRP.
By definition, QoL would be additionally surrogate for OS if treatment effect on QoL predicted a survival benefit.
This would suggest that song would be a better surrogate for sexual selection at the phenotypic level.
We would therefore expect that the countywide average for such components would be a poorer surrogate for personal exposure.
Jones said it was the EPA's assessment that honeybees would make a good surrogate for other species.
In 2012, Pollard said she would act as a surrogate for Winston and Debra Kaba, who were unable to conceive after the birth of their first child.
Considering the longer turnaround time (TAT) of susceptibility testing and culture results, DNA-based ESBL identification would be a valuable surrogate for phenotypic-based methods.
(Note that if we did not know the index genotype, the affected relative's genotype would act as a surrogate for it.
With a predictive IVIVC, in vitro dissolution would not only be a tool to assure the consistent performance of the formulation from lot to lot but would also become a surrogate for the in vivo performance of the drug product.
Using only distant recurrences would provide a better surrogate for death from breast cancer, but their use requires longer follow-up, and it is too early to use this end point at this stage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com