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Although there could still be some unmeasured confounders or residual confounding from modelling or measurement errors, we believe their presence and effect would not be considerable because of extensive adjustment for several known confounders.
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Once sample mix-up affected a data set, mere re-reading of electropherograms would not be sufficient, but considerable efforts (including re-amplification and re-sequencing) are needed to cleanse the data from all potential artificial recombinants.
Also, the dose used for this initial evaluation was considerable and would not be practical if scaled up for use in humans.
When I needed to leave Tahrir Square today, several Egyptians guided me out for almost an hour through a special route so that I would not be arrested or assaulted — despite considerable risk to themselves.
If James Randi had serious concerns about fraud and deception in medicine and science, one would think that he would not be silent on the rampant chicanery considerable fraud regularly committed by conventional medical and "scientific" researchers and by Big Pharma companies.
For example, in the search for a cancer biomarker, considerable effort would not be exerted to further study acute phase response proteins, although many of these would probably be detected as having higher abundances in samples taken from cancer-affected individuals.
One could assume a very high exponential factor, but that would predict only the beginning of the experiment; however, as inhibition came into effect, the decrease in the growth rate to zero would not be slow and gradual, but very considerable and rapid.
But there is a considerable risk that airstrikes alone would not be enough to strip Iran of its nuclear program.
And a merger would bring considerable economies of scale.Yet buying Clear Channel Outdoor would not be easy.
This means that such a study would require considerable time, manpower and funding, and the results would not be timely.
This would not be a catastrophe, the annuity puts her back on track after 15 years, but it would be a considerable inconvenience.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com