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Exact(6)
Based on this observation, we predicted that the human and Drosophila lamins would have conserved interaction partners.
Through this sampling procedure, given the frequency of NMD events in human, we found that only 1.3(±2.3) AS-NMD candidates would have conserved AS-NMD candidature by chance between human and rat (32 conserved cases are observed, Table 2).
The analysis based on the conservation of individual binding sites, however, does not address the question whether a promoter or enhancer, which typically have multiple binding sites, would have conserved functionality or not, as the gains and losses of binding sites in the neighborhood may compensate each other so that the overall affinity remains largely unchanged [56], [64], [65].
With such high levels of sequence identity it may seem reasonable to expect that many orthologs between mouse and human would have conserved functions.
Thus, if we knew the assembly pathways of these complexes, we could assess whether the evolutionary fusion events were compatible with the existing order of assembly and would have conserved that order.
These two genes are essentially identical in the regions encoding the signal sequences and autotransporter domains, and could arguably have evolved by a gene duplication event, that would have conserved this motif without selection.
Similar(53)
If so, and if orthologous genes have conserved function, we would expect a slow rate of organ-specific expression evolution.
This suggests that vertebrates could have conserved ancestral exon-intron structures, while most other phyla would show derived patterns.
But we have conserved the character of that design.
Instead, HSA 1 would have been conserved as a single chromosome in the ancestral complement, because it was conserved as such in the Eutherian ancestor and in three species of Xenarthra (C. hoffmanni, B. torquatus, and B. tridactylus), and must have been convergently split in the karyotypes of the other species of the group, as already demonstrated for other placental mammals [ 43].
Since deforestation in treated areas was so low (0.8 % per year), the authors also suggested that some of the forests would have been conserved regardless of compensation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com