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Because the Hawking emissions would be obscured by more powerful radiation sources in space, it would be difficult to observe with astronomical instruments.
Furthermore, the conformations of the binding peptides, as well as the energetic contributions to total binding free energies are analyzed to reveal the physical mechanisms of the interactions, which would be difficult to observe using experimental approaches.
There may exist a multiscale structure of stable patches behind them, but it would be difficult to observe this complex structure within the limited period of the seismic cycle (Uchida et al. 2016).
Since CNP are very small, we expected that it would be difficult to observe their distribution in animal organs by conventional microscopy, but surprisingly, DN, GN, and GO formed agglomerates that could be seen even by the naked human eye (Figs. 4a e, 5a e, i, 6a e, 8, and 9).
This is not unexpected since it would be difficult to observe a change in protein concentration above the background of these proteins found in ribosomes in eukaryotic tissues.
The incidence of malignancy is so high in each group that it would be difficult to observe a statistically significant difference between subgroups in this size study population.
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Even here we observed a level of background morphologic changes in the NIH 3T3 cells such that low levels of transformation would be difficult to detect.
"It would be difficult to keep that under wraps".
Such stars would be difficult to detect.
Moreover, weak selection would be difficult to detect as well.
The use of nonlinear functions provides a concise measure of a variety of physiological traits associated with growth and development that would otherwise be difficult to observe.
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