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For these analyses, the hypothesised difference, that is, the smallest worthwhile difference, was calculated as 0.5×the between-subject SD.
In this context of a higher rate of biopsy or monitoring, the clinically worthwhile difference was altered to a 15% difference (an odds ratio of 1.8) from 45% to 60%.
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The student should think what price difference is worthwhile to go to their ideal school over their second choice.
If the price for the store version is $3 and the Girl Scout version is $5, you can perhaps argue that the fair market value is $3, and you are making a deductible donation of $2. (It probably wouldn't be worthwhile, though, unless the price difference is really substantial, or you bought a lot of Girl Scout cookies).
Does it really matter whether there is a statistical difference between two treatments if the difference is not clinically worthwhile or if the research is marred by bias?
A 20 percentage point difference in MUVD was chosen because in our judgement such a difference would be clinically worthwhile and the effects on CMD suggest that such a difference is plausible.
A small snippet of making a difference is what makes all the hard work and heartache worthwhile.
Being able to make a difference is powerfully enlivening; it makes our lives feel more worthwhile.
Therefore, after a consensus discussion with the OTs delivering the trial interventions, we estimated a worthwhile difference between groups to be 20%.
Future cryopreservation studies should be adequately powered to detect clinically worthwhile differences in cumulative live birth.
Differences are significant and consistent with the hypothesis, suggesting that tests at other hierarchical levels may be worthwhile.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com