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"We saw some of the worst responsiveness to increased incentive spending we have ever seen," he said.
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∆SV-PLRTE > 13% [AUC ± SD: 0.96 ± 0.03] had the highest accuracy, while ∆SV ≥ 10% [AUC (95% CI) 0.57 0.34 0.78)] had the worst accuracy to predict fluid responsiveness in mechanically ventilated patients in a spontaneous mode (3 studies totaling 77 patients) (Additional file 1: Figure S2).
∆VSP of 52% [AUC ± SD: 0.98 ± 0.03] [16] had the highest accuracy and cIVC > 42% [AUC (95% CI): 0.62 (0.66–0.88)] and IVCmax < 2.1 cm [AUC (95% CI) 0.62 (0.49–0.75)] the worst accuracy to predict fluid responsiveness in spontaneous breathing patients without ventilatory support (12 studies totaling 572 patients) (Additional file 1: Figure S1).
Responsiveness using the BPI average pain or worst score to define responders was not assessed owing to the small sample size.
Thus, responsiveness is strongest for the BPI-SF worst pain item and FACT-P followed by the BPI-SF average pain item in clinical trials evaluating recently approved treatments for patients with mCRPC.
Pain and prostate cancer–specific HRQOL measures supporting claims met US regulatory standards for construct validity, reliability, and responsiveness; these properties were strongest for the BPI-SF worst pain item.
But the fact that geographic diversification failed so miserably despite the relative concentration of the worst housing bust effects suggests that the bigger problem with mortgage lending isn't the responsiveness to local conditions, but rather the general brittleness of the system as a whole.
Patients are anxious, dread the future, lose responsiveness to the environment, have insomnia, lose appetite, there is a diurnal variation with depression at its worst in the morning.
Responsiveness is a problem".
I appreciate their responsiveness.
Responsiveness can't be faked.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com