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While proponents say the worst difficulties are behind the program and that it eventually will prove its worth, NASA has begun to explore alternatives it hopes will lead to a new generation of space vehicles.
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Using a 10 cm visual analogue scale (VAS) participants were then asked to indicate how difficult this thing was (0 = "no difficulty", 100 = "worst imaginable difficulty").
But the biggest European surprise was a strong increase in sales to some countries suffering the worst economic difficulties.
The sector was last year's worst performer.The difficulties facing investors when selecting individual mutual-fund managers are well known.
According to the official history of Australia in the war, Wrigley and his predecessors could hardly do more than "retard the centrifugal forces affecting Australian disposition, and repair the worst administrative difficulties arising from wide dispersion".
Phosphylation of the active serine site leads to an accumulation of the synaptic ACh concentration, followed by overstimulation of cholinergic receptors and disorder of numerous body functions such as salivation, lacrimation, tremors, miosis, diarrhea, and, at worst, respiratory difficulties and death due to anoxia.
One example is the "Rigidity of Employment Index," which measures between 0 (the best) and 100 (the worst) the difficulty in hiring and firing workers, and also measures mandated benefits, such as vacations, and restrictions on working hours.
While the worst of the difficulties are said to have been in Lincolnshire, supermarkets and growers elsewhere in the country have disputed the claims, describing this year's weather as ideal for pumpkins.
Worst: Various technical difficulties.
A standardized rating of 1 represents the worst possible function (extreme difficulties, constant fear, extreme distress) and a rating of 7 represents the best possible function (no difficulties, no fear, no distress).
Coincidentally, it was exactly two years ago yesterday that Interpublic first disclosed signs of the problems that subsequently grew into one of the worst bouts of financial difficulties and accounting irregularities ever to plague a major agency company.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com