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The descriptors provided to the patient were a compilation of the respective best and worst descriptors for each health component used in the Assessment of Quality of Life (AQoL) instrument[ 41].
The performance of the descriptors is similar to that seen when the compounds with unknown interactions are included, with two exceptions: the GCUT with Property descriptors perform much better and are the second best descriptors, and the Property descriptors are the second worst descriptors when the clusters with at least three compounds are considered.
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GLCM is among the worst performing descriptors for all datasets, except for the Mondial Marmi dataset.
To examine this, the first ANOVA investigated the main effects of Description (A versus B) and sequence (i.e. whether participants were in the group who received best or worst health descriptors first), and an interaction effect between them.
(A) Shown are the best performing descriptor (Z-Scales (3) and Z-Scales (Avg)), and (B) the worst performing descriptor (ProtFP (Feature)).
(A) Shown are the best performing descriptor set in the ACE inhibitor experiment (Z-Scales (Binned)), and (B) the worst performing descriptor set (ProtFP (Feature)).
The worst performing descriptor set is ProtFP (Feature) (RMSE 0.627 log units and R02 0.566).
Shown are (A) the best and (B) worst performing descriptor sets.
MBP is the by far the worst performing descriptor followed by GLCM.
Figure 8 PCA plots of the best and worst performing descriptor sets on the NNRTI benchmark.
The worst performing descriptor sets were found to be (in descending order) ProtFP (PCA3) and Z-Scales (Binned), Z-Scales (5) and ST-Scales.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com