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Worst case, intention to treat, analysis found dimeticone was significantly more effective than malathion, with 30/43 (69.8%) participants cured using dimeticone compared with 10/30 (33.3%) using malathion (p<0.01, difference 36.4%, 95% confidence interval 14.7% to 58.2%).
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Missing data were handled using a "worst case" intention-to-treat analysis in which patients with any missing component of the Mayo Score were considered not to be in clinical response, clinical remission, or to have mucosal healing.
Surprisingly, the expectation that assuming worst case scenarios and hostile intentions from others would predict reactive aggression was not confirmed by the present study.
Moreover, even if they did it only for beautification purposes (in the worst case scenario) and had no intention of seeking a job afterward, they wouldn't look so characteristically homeless.
As we have seen in major data breaches such as the Sony hack, the worst case scenario really depends on an attacker's intentions and the magnitude of the target.
However, the intention to treat principle was violated in this trial, so a worst case analysis was conducted in which the difference in remission rate compared with citalopram was no longer statistically significant.
Up to 20% of the patients can be expected to be lost to follow-up in the worst case scenario, so that, finally, 792 patients will be analysed according to the intention-to-treat principle.
Worst case?
That's the worst case".
"The worst case?" Mr. Bloomberg said.
Worst case: Civil war.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com