Those with baseline HbA1c <8% at baseline had worsened control at 12 months of follow-up (mean change = 0.06%), whereas those who had HbA1c ≥8% at baseline improved over 12 months by 0.5%.
In a study conducted in severe asthmatics controlled on high-dose ICS and other therapies including theophylline, withdrawal of theophylline was shown to worsen control of disease, while re-treatment restored asthma control, suggesting utility in using this drug to augment treatment 98.
Despite concerns of adherence and problems with doctor availability, these findings suggest home delivery of medication and monitoring by CHWs (rather than nurses) did not worsen control of hypertension; instead the benefit of not having to travel to the clinic, as well as perhaps the care provided in the home setting, led to better control.
We separately modeled predictors of worsened glycemic control and worsened cholesterol control using multivariate regression modeling after assessing correlations between predictor variables.
Conversely, since increased reliever use is an indicator of sub-optimal control in asthma, it could have a similar significance in COPD, reflecting worsening symptom control or an impending exacerbation.
Causality is not established, but rather, the picture is confused, with some antidepressants linked to worsening glucose control, particularly with higher doses and longer duration, others linked with improved control, and yet more with mixed results.
The Pew Research Centre released a report this month, Digital Life in 2025, that predicted worsening state control and censorship, reduced public trust, and increased commercialisation of every aspect of web culture.
Understanding the effect of worsening asthma control on expenditures and health resource utilization (HRU) is important.
This patient presented with worsening BP control and abdominal fullness.
