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After the worldwide vaccination program conducted by the World Health Organization (WHO), smallpox was eradicated in 1980 [1], and soon after eradication general vaccination with Vaccinia virus (VACV) against smallpox was discontinued.
There fore, a worldwide vaccination program was launched with very strong confidence [ 4].
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Even if the cost-effective analysis is essential in order to diffuse the vaccination in males, the Foresta's study increases our knowledge in the direction of male vaccination program worldwide approval.
The worldwide implementation of vaccination programs against HPV began only a few years ago, and their long-term efficacy in the prevention of cervical carcinoma is not yet completely assessed.
Despite a widespread vaccination program, over the past fifteen years was seen a return of pertussis worldwide [ 1].
Chronic HBV infection is a major contributor to morbidity and mortality worldwide despite the availability of efficient vaccines and vaccination programs in China and elsewhere [ 52].
Of note, rotavirus vaccines were recommended worldwide by the WHO in 2008; however, these have not been a part of routine Saudi vaccination program until 2013.
The large-scale vaccination with live vaccinia virus (VACV) that led to the worldwide eradication of variola virus (VARV), the causative agent of smallpox, is often cited as the most successful vaccination program [1].
However, the vaccination program faded away and, in the end, only about 37,000 were vaccinated.
Since 2009, pneumococcal vaccines with broader coverage have been licensed and will be introduced into vaccination programs worldwide.
But what if such a broad vaccination program is impossible?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com