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An additional drawback is a run-time complexity of O(n 3), which makes the method inefficient for working with datasets containing thousands of points.
Since working with datasets is such a central task in cheminformatics there are a lotof potential additional features which could be included in future versions of MONA.We are confident, that MONA's functionality will be substantially extendedover the next year.
A global criterion is not ideal for preventing any erroneous annotations, but is required when working with datasets of this size.
There was considerable evidence favoring the Student t mixed model for data sets simulated under Student t processes with limited degrees of freedom, and moderate advantages associated with using the Gaussian mixed model when working with datasets simulated with 50 or more degrees of freedom.
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Everyday we work with datasets from around the world.
It also is built to complement other Big Data solutions companies might already be using and is able to work with datasets of any size or type, the co-founders tell us.
It is designed to work with datasets that contain hundreds of thousands to millions of SNPs.
AKB was responsible for obtaining the tax parcel datasets, working with the dataset owners to ensure appropriate use of the datasets, and assisting MJS and CS with GIS activities.
Silicon Valley may have coined the 'big data' buzzword, but genomic scientists have been working with massive datasets for decades.
More importantly, MONAoffers a different way of working with molecule datasets.
We used SATé [ 22, 23] combined with either MAFFT [ 18] or PRANK [ 24] alignment algorithms, depending on the limitations of working with large datasets.
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