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The screen data observed in this study provide workable assumptions on the natural history of DCIS and do not lead to a major difference in conclusions regarding overdiagnosis.
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Although this seems like a straight forward procedure, it requires various considerations and assumptions to be workable, in particular with respect to the question of how to assign the true evolutionary origin of a given gene.
P versus NP has enormous practical and economic importance, because modern cryptography is based on the assumption, which is workable so far, that P does not equal NP.
While it seems evident that low dose radiation protection standards must be revised, since the current LNT assumption is clearly inappropriate, defining a workable set of standards that actually reflect the biology may be difficult.
Research from several specialties within psychology has demonstrated that when we are faced with a new or surprising situation, we rely on some basic assumptions to simplify affairs and find a workable explanation.
The application of the remaining parameters in the model are described in the appendices, while the assumptions that are required in order to develop a workable model structure and enable the analysis to be carried out are described in Table 3.
For one thing, they applied quantitative measures to capacities and qualities in their work, and even if this was in no way observational, and involved no attempt to actually develop workable systems of measurement, they expanded the conceptual repertoire beyond the Aristotelian assumption that nothing could be measured other than space, time and motion.
The Court disagreed with the lower court's assumption that the university's "serious, good faith consideration of workable race-neutral alternatives" was sufficient to justify the consideration of race in university admissions.
I've found that our greatest miscalculations revolve around two assumptions: 1), believing that we did enough due diligence to have a workable understanding of the major legal issues associated with operating a food production company and a food truck and 2), thinking we had the time, money and help necessary to truly get up and running.
These assumptions are understandable, as devices to simplify the models enough to make them workable.
In the 1950s it was Mr Samuelson who had rediscovered the pioneering early work of Louis Bachelier, a French mathematician whose insights would later underpin the Black-Scholes option-pricing model; and it was Mr Samuelson who suggested the assumption, that share prices move according to geometric Brownian motion, which makes this model workable.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com