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Indeed the performance is greatly influenced by the quality of the expression data, the quality of the protein network around the actual disease gene, and the underlying biology (i.e., existence of actually disrupted expression modules) so that the method cannot be expected to work optimally on every disorder.
QRNA v.1.1 [ 14] was used to score the alignments for noncoding RNA potential using settings determined to work optimally on a test set of ncRNAs embedded in random alignments of equivalent sequence identity (default settings with -w 100 -x 50).
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The solving of situational problems for determination of these time intervals when the satellite instruments work optimally is a very important part of all activities on every stage of preparation and realization of space missions.
(Temporary) inability to work optimally due to health problems causes high productivity loss, and poses a great burden on individuals and society [ 1, 2].
For this plan to work optimally, people have to be willing to give up more and more personal information to Facebook and its partners.
But what Levi's was unprepared for was the fact that the company's IT operation could not get its multiyear, multimillion dollar investment in SAP's business software to work optimally.
And for any drug treatment to work optimally, otherwise healthy patients should also adopt protective habits, including eating diets rich in fruits, vegetables and low-fat dairy products and low in fat and salt and other sources of sodium.
When it works optimally, the Universal Service Fund seeks to be the placeholder for when markets don't work optimally.
The full-field transparent form factor is really what lets the software work optimally though, offering the best UX.
Plus, it's been tested to work optimally even with older versions of Android, including 2.2 and higher.
Another aspect is the possibility to use the efforts of collaborative work optimally.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com