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Nevertheless, before carrying out in vivo studies, some work on optimization of the manufacturing process and post-processing is required.
Therefore, we constantly work on optimization of codes and methods and on providing sufficient access to the most powerful computer systems available.
Moreover, the frequency of CM interval affects the system availability and the literature shows that there is limited work on optimization of CM interval.
Considering importance of PUFA in human health and suitability of microbial sources, many researchers have published work on optimization of PUFA production from microorganisms [ 10, 19, 20].
Our initial work on optimization suggested that the number of haptens covalently attached to BSA and the concentration of unreacted haptens in solution may influence protein yield.
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Further, Baidu and Nvivia will work on optimizations for Baidu's PaddlePaddle open source deep learning framework for Nvidia Volta, and will make it broadly accessible to researchers and academic institutions.
Melo et al. (2009) worked on optimization of supply chain performance by determining optimal location.
At Mount Sinai, G.E. has worked on optimization and modeling software that enables admitting officers to see beds and patient movements throughout the hospital, to help them more efficiently match patients and beds.
Lee Altenberg worked on optimization algorithms in genetic programming and defined evolvability as "the ability of a population to produce variants fitter than any yet existing" (Altenberg 1994).
Kumar et al. (2015) and Sharma et al. (2015) also worked on optimization of process parameters using response surface methodology and desirability function.
Having a broader scope, the analyses presented in the present paper are based on a repository maintained by the international community, in which prediction and clustering works are also included (besides works on optimization).
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