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PRF may result from liberation failure (i.e., the inability to ventilate spontaneously without ventilator support) or extubation failure (i.e., the inability to tolerate removal of the endotracheal tube) or both [ 5].
Table 3 Factors significantly associated with the number of days alive without ventilator support by day 90 Parameters Number of days alive without ventilator support by day 90.
In the learning cohort, 211 of 405 patients were "alive and without ventilator ≥20 days within the first month".
"Alive and without ventilator ≥20 days within the first month" and "ARDS" were analyzed using multivariable logistic regression analysis.
Ventilator-free days were defined as patients being alive and breathing without ventilator assistance up to day 28.
Additionally, an analysis of the endpoint "alive and without ventilator ≥20 days within the first month" was performed.
Similar(32)
They still cannot walk or breathe without ventilators.
I asked Jackie Banda, the doctor in charge of the unit that day, how long the unit had been without ventilators.
Fig. 1 Kaplan Meier analysis showing the percentage of survival between patients with and without ventilator-associated pneumonia.
The mortality rate of patients who developed ventilator-associated pneumonia (45.5%) was significantly greater than the mortality rate of patients without ventilator-aquired pneumonia (32.2%, p < 0.004).
In accordance with our findings, Bonten et al. [ 23] showed that ventilator-associated pneumonia in patients with severe sepsis and septic shock was accompanied by increased levels of IL-6 and IL-8 at the time of diagnosis, and even two days after diagnosis, compared to control patients without ventilator-associated pneumonia.
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