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But can powerful autocratic regimes really be accommodated in global economic institutions, without undermining either their own autocratic powers or the liberal democracies?
There is no universally accepted definition of these designs, but a working definition might be "a multistage study design that uses accumulating data to decide how to modify aspects of the study without undermining the validity and integrity of the trial".
VOC OHM successfully couples the typical VOC and CRM experimental set ups without undermining the PTR-MS's ability to measure either parameter.
The definition given here of "a clinical study design that uses accumulating data to decide on how to modify aspects of the study as it continues, without undermining the validity and integrity of the trial," is often quoted as definitive.
109 There is increasing interest in adaptive designs for clinical trials, defined as the use of accumulating data to decide how to modify aspects of a study as it continues, without undermining the validity and integrity of the trial.
In [ 1] adaptive designs are defined as: "...a clinical trial design that allows adaptations or modifications to aspects of the trial after its initiation without undermining the validity or integrity of the trial.
Last, in the framework of PRO data, adaptive and sequential designs eventually incorporating samples size re-estimation [ 18] might also offer a valuable tool by using accumulating data to decide how to modify some aspects of a study as it continues without undermining its validity and integrity.
How can we use information without undermining privacy?
How does one root for Solidarity without undermining arms control?
They tried to expand the regional economy without undermining apartheid.
To put more pressure on North Korea, without undermining it.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com