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No one can imagine the economy of London in the 18th/19th/20th centuries without the circulation of people between other places and London, other parts of the UK and London, and now increasingly other parts of the world and London.
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How can we write without the old serious publications, make movies without risk-taking Hollywood producers, live without cheap urban housing, discover art without the underground, make a career without the circulation-desk jobs?
But no more than 20percentt can be plugged without impeding the circulation of the steam — and less in some cases — before the generator has to be changed.
Body and extremities should be positioned without restricting the circulation and avoiding any bruising, strains or avulsion in the body structures.
The retention strips and the suction cups fix the animal's paws on smooth surfaces without impairing the circulation, immobilizing them on the ground during bathing, grooming, nail clipping, and clinical examinations.
However, in pulmonary resection surgery, the main concern is still the development of acute lung injury and ARDS [ 11], which is why the main purpose of implementing BGDT was to avoid hypervolemia by restricting fluid administration without compromising the circulation and oxygen delivery.
Elevated LBP level was suggested to be related to bacterial passage from the gut to the circulation without overt infection in cirrhotic patients with ascites on the basis of the fact that patients with increased serum LBP level were four times more likely to have severe bacterial infection during follow-up than patients with normal LBP [51].
Mice infected with P. berghei ANKA were injected intraperitoneal with either control PBS, IgG, or anti-CD14 antibody (days 1 and 5 post infection) to clear monoctyes from the circulation without affecting other blood cells (complete blood counts in Supplementary Figure S2).
These results indicate that carboxy-PTIO attenuates LPS-induced hypotension, metabolic acidosis, and hypoxia by scavenging excess NO from the circulation without affecting NO synthase (NOS) activity.
It is believed, however, that these limitations of the IPML setup were counter balanced by the advantage of specifically isolating lung-derived mediators released into the circulation, without the confounding contribution of systemic factors to the development of inflammation.
Abraxane®, an albumin-stabilised nanoparticle formulation of paclitaxel, has also the ability to effectively deliver paclitaxel to the circulation without Cremophor EL, but has the disadvantage of i.v. use.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com