Sentence examples for without substantial modification from inspiring English sources
Automobile assembly plants did not readily accommodate airframes, nor could an automobile engine factory be converted without substantial modification.
The automated routine described above can be applied to any number of tilt series without substantial modification, just by considering them as a unique dataset/series.
This may seem trivially obvious, but resolving such inconsistencies without substantial modifications to either method or theory (or both) is anything but.
However, it suffers from relatively low production rates and poor control of fiber alignment without substantial modifications to the fiber collector mechanism.
This means that it cannot be expected that the sustainability targets defined for the German energy system will be achieved by 2020 without substantial modifications of political strategies and measures implemented so far.
In our study we show that the existing models that have been investigated are not suitable for reuse without substantial modifications.
However, many common types of structural variation can only be detected by exploring read alignments to repeat sequences in genomes, and these existing tools are not easily adapted to haploid microbial genomes without substantial modifications and optimization by the end user.
Currently, these methods can not be reproduced directly within an i2b2 hive without requiring substantial modification to the underlying code (potentially developing a new cell).
Note that because appending indels as bubble branches does not (by itself) require a change in the BWT backwards search algorithm, existing aligners (e.g. BWA) could use this technique to handle longer indels without a substantial modification to their code.
The strengths of our study are that annual DHF incidence and case fatality ratios have been documented continuously for 45 years, using the same WHO case definition and case classification of dengue, based on both clinical and laboratory diagnostic criteria without any substantial modification throughout the surveillance period.
For the existing gun systems without making substantial modifications, MRS could be useful in controlling the deflections of gun barrels with estimation/prediction algorithms.
