60% had non-specific malnutrition, 8% had protein-energy malnutrition, and 32% without malnutrition.
Secondary objectives: To describe nutritional status on the basis of simple anthropometric parameters and to characterize the profile of patients with and without malnutrition.
CR, reduced caloric intake without malnutrition, is a dietary intervention that increases life span and reduces aging-related pathologies in eukaryotes from yeast to primates.
The exposure of interest, malnutrition, was determined in patients at risk for malnutrition via a Registered Dietitian formal assessment within 48 hours of ICU admission and categorized as non-specific malnutrition, protein-energy malnutrition, or without malnutrition.
Further, in survivors of hospitalization (n = 1,424) patients with malnutrition at ICU admission have a 50% increased odds of 90-day post discharge mortality [adjusted OR 1.52 (95%CI 0.99-2.37), P = 0.059] and a 40% increased odds of 365-day post discharge mortality [adjusted OR 1.45 (95%CI 1.02-2.05), P = 0.035] compared to patients without malnutrition.
Further, in survivors of hospitalization (n = 1,223) patients with protein-energy malnutrition at ICU admission have a 2.8 fold increased odds of 90-day post discharge mortality [adjusted OR 2.77 (95%CI 1.49-5.17), P = 0.001] compared to patients without malnutrition.
Certainly, in the quest to find protocols for DR in worms that mimic those used for mammalian studies, complete removal of food does not fulfill the criterion of 'under nutrition without malnutrition' [1] and may in part invoke worm-specific starvation responses that may or may not translate to the vertebrate DR paradigm.
ER is to reduce moderately nutrient availability without malnutrition.
CR refers to a reduced calorie intake without malnutrition.
On the contrary, an individual could be thin with a low BMI but without malnutrition.
Dietary restriction (DR) without malnutrition is widely regarded to be a universal mechanism for prolonging lifespan.
