Sentence examples for without major alteration from inspiring English sources

This outcome accords with subtle mutations like Cx32V84I [31] and Cx26V84L [32] imparting a pathological phenotypes without major alteration in the unitary ionic conductance [33].

Handouts and protocol sheets for home practice were taken from the manual without major alteration.

However, the proposed formulation can easily cater for other design codes without major alterations.

The bill now heads back to the Chamber of Deputies, which is expected to approve it without major alterations.

The original bridge at Commercial Road is buried beneath the new embankment, and so there is sufficient headroom available through the embankment without major alterations to the road level.

Typically, the outer retina mainly formed by photoreceptor cell bodies and their inner and outer segments degenerates and subsequently vanishes without major alterations of the inner retinal layers.

CD4 was chosen since it shows low variance in its distribution and is uniformly present without major alterations through the entire lifespan of CD4 T cells.

Each panel member assessed each item using four categories: not relevant, unable to assess relevance without major revision, relevant but needs minor alteration, and very relevant.

We found a similar relationship, with a long-lived strain (OR) producing fewer mtROS than short-lived strains (DAH and CS), without a major alteration in oxygen consumption.

Inclusion criteria were (i) mechanical ventilation, (ii) >18 years and (iii) expected to stay on mechanical ventilation in the ICU without any major alteration in treatment for the next 48 h.

This feature may prove valuable in a number of instances; e.g., to relax ligand-receptor complexes without causing major alterations of their original geometry, or to perform a torsional scan on a selected dihedral while relaxing the rest of the molecule.