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This approach was taken because mutations detected in a conserved region for multi-copy genes could not be assigned to a specific copy without further validation (Table 5).> -wrap-foot> Based on the validated mutants and the known mutants detected from previous study [ 40].
Thus, this large-effect QTL region could be directly used to develop high-yielding lines for the TPE without further validation.
In addition, these yield-related QTLs identified in the TE could be directly used to develop high-yielding rice lines suitable for rainfed rice ecosystems, without further validation or testing.
Some of these simulations may be questionable without further validation, such as the predictions of cytosolic and mitochondrial phosphorylation and redox potentials (Fig. 5).
Some instrument developers have made modifications after publishing the instrument, seemingly without further validation (e.g. MMAA, MMT-R).
Longitudinal evidence without further validation yields biomarkers of age, so we checked the literature for deleterious or beneficial effects.
Similar(41)
The onco-protein c-fos was previously linked to favorable prognosis of gastric cancer (GC) without further validations.
It must be noted that the survival benefit of these specific interventions has been demonstrated in only a single RCT for each intervention [ 2, 3, 63], without any further validation or confirmatory trial.
In contrast to previous methods that identify pathways across a set of samples without any further validation, we show that mutated pathway-groups can be found in each breast cancer subtype and that such groups are invariant across the majority of samples.
These mPT results indicated that traditional clotting time assays may not be suitable for assessing the effect of direct factor Xa inhibitors without modification and further validation.
Therefore, our approach could be used for quantitative micromechanical measurements without the need to perform further validation via bulk compression experiments.
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