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pH step elution protocols are derived from model calculations without further optimization experiments necessary.
The multi-threaded runs ran on all four cores without further optimization of Scala's parallel collections settings.
Thus, after the parameter search process, the resulting EFS system may synthesize new features for the rest of the (unseen) data without further optimization processes.
However, such an optimization heavily depends on the graph structure, and evaluations in [10] and [11] have shown that evaluations are obtained in the range of seconds without further optimization on a graph's structure.
Better result was achieved finally to get benzyl ether 8c through 2,4,6-tris(benzyloxy -1,3,5-triazine (Tribenzyloxy -1,3,5-triazineOH in one-pot (65 % total yield without further optimization) (Scheme 3).
(III) NH4OAc, NaOAc, EtOH, MW, 40 °C, quantitative conversion Open image in new window Scheme 6 On-going synthetic perspectives of acortatarin A. N-alkylation of pyrrole 11 with iodide 14b could deliver hemiacetal 12b (Cs2CO3/MeCnearly nearly 1/1 diastereoisomers, 60%% yield without further optimization).
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An initial study [ 7] suggested that the tested XML database configurations without further optimizations were not suitable as persistence mechanisms for openEHR-based systems in production if population-wide ad hoc querying was needed.
A rhIFNα2b fusion protein of 37 kDa in size was produced in high expression levels relative to total protein, renatured and purified from IB with a yield of 3.46 mg/l without any further optimization.
The proposed procedure is based on the naïve Bayes approximation, therefore, the optimization of necessary parameters is performed only once and separately for each variable, thus resulting computationally fast, while later steps of the procedure enable to calculate more complicate models and choose the best one, without any further optimization.
All the above experiments used features without any further optimization.
The threshold of 200 Da has been chosen ad hoc and without any further optimization; we expect that choosing, say, a threshold of 100 Da will not result in significant differences.
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without further optimizing
without extensive optimization
without further discussion
without further explanation
without detailed optimization
without global optimization
without further ado
without major optimization
without further research
without further penalty
without systematic optimization
without significant optimization
without recursive optimization
without additional optimization
without manual optimization
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