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Without further optimisation on the reconstruction (i.e. bundle adjustment), the error obtained is observed to be within a similar range as previous works [20, 22].
The best scored haplotype inference was selected without further optimisation with regard to genotype inference.
Without further optimisation, the present synthesis generates a product with a modest specific activity of 10 GBq/mg (1 GBq/μmol) when starting with 12 18 GBq F. A likely scenario for production for human use is as follows.
However, while this is clearly insufficient, preselection of a clinically relevant risk population such as BRCA1 or BRCA2 mutation carriers (Antoniou et al, 2003, 2008) could raise the PPV to ⩾10% without further optimisation, simply because of the higher prevalence in this collective.
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Moreover, without any further optimisation the Cyclops performs good with other spray dried aminoglycosides such as kanamycin and amikacin too.
Therefore, further optimisation of inoculum density is crucial.
Further optimisation may allow assessment of reasonable timeframes to achieve technical remediation.
There are many technical aspects that need further optimisation in cardiac CT perfusion imaging.
Further optimisation in terms of sensitivity and time resolution should be made for broader applications.
Based on these evaluation criteria, further optimisation of the beads would appear relevant, especially when dealing with high BAM concentrations.
This research provides proof of concept for further optimisation of organo-mineral fertiliser manufacture using readily available lignite resources.
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