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Among 69 patients with early-onset or familial clear cell renal cancer without further characteristics of BHD, germline FLCN mutations were found in 4% of cases (Woodward et al, 2008).
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In any case, these proteins could be interesting targets to address in future studies, presently these molecules remain still at a speculative level and are difficult to discuss without further pathological characteristics related to these molecules.
Additional file 1: Further characteristics of patients with and without diabetes sub-divided into BMI groups.
Table 1 gives further characteristics of participants.
Further characteristics are shown in Table 1.
Further characteristics are described in Table 3.
If the classification of CADASIL in the ICHD-II was not revised, clinicians will be induced to commit a formal error defining the headache as migraine or omit useful clinical details attributing the headache to CADASIL without giving any further characteristic.
They then use different methods to select "likely voters" -- those who indicate they are likely to vote -- without further adjusting their characteristics.
While the use of epistasis-based hypotheses to make general assumptions on the evolutionary dynamics of viral populations is appealing, our data caution their interpretation without further knowledge on the characteristics of the viral mutant spectrum under different environmental conditions.
A study dealing with esophageal squamous cell carcinomas describes a higher GRP94 protein-expression in carcinomas compared to normal esophageal mucosa without further correlation to pathological characteristics [ 14].
For the remaining 8468 patients, only baseline characteristics were assessed without further follow-up.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com