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Patients with acute dengue had statistically significantly lower leukocyte and platelet counts than patients without dengue.
Most of the dengue case-patients (61%) had a pretravel encounter, a significantly higher percentage than for ill returned travelers without dengue (53%; p<0.005).
In our study population, rash was the only clinical symptom significantly more frequently observed in patients with confirmed dengue infection when compared to febrile travellers without dengue.
Odds ratios and 95% confidence intervals (CI) were determined for the comparisons of clinical and laboratory features of travellers with and without dengue infections.
Table 1 summarizes the clinical features of 69 travellers with confirmed dengue infection in comparison to 1,035 febrile travellers without dengue infection.
The mean values of the indices calculated at the health area level were also ≈1 for areas with or without dengue cases during the subsequent epidemic.
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Evidence for recent DENV infection was 7.3× more prevalent among those with than without dengue-like illness.
When comparing patients with and without dengue-infection, there was no significant difference in the frequencies of major symptoms except in the occurrence of a skin rash (23.5% vs. 9%, respectively, p = 0.0001).
The age distribution of patients with and without acute dengue is shown in Figure 1.
The clinical features of patients with and without acute dengue are detailed in Table 1.
Comparing patients with and without acute dengue infection, no significant difference was seen in the median length of travel (28 vs. 24 days, respectively, p = 0.083, Mann-Whitney test) or the median age of the patients (32 vs. 33 years, respectively, p = 0.58, Mann-Whitney test).
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CEO of Professional Science Editing for Scientists @ prosciediting.com