Sentence examples for without constitutive from inspiring English sources

Searle espouses a weaker form of force conventionalism than does Austin in leaving open the possibility that some speech acts can be performed without constitutive rules; Searle considers the case of a dog requesting to be let outside (1969, p. 39).

We found that TNBC cell lines without constitutive activation of Met were sensitive to EGFR TKIs in culture.

Thus, in ER-positive cells without constitutive ras/MAPK signaling (i.e. MCF-7), TGF-β primarily induces a robust cell cycle arrest program (Figs 4 and 7c).

[ 29] When injected subcutaneously into athymic mice, administration of IL-1Ra reduced tumor growth of IL-1-expressing tumors but not of tumors without constitutive IL-1 production.

The precise roles of tamoxifen are complex: although it competes with 17β-estradiol to bind to ERα, ERα bound to tamoxifen is still able to target the TFF1 (also called pS2) promoter without constitutive activation of gene transcription.

In our assay, the reporter has 5X Gal sequence upstream of constitutive CaMV 35S promoter; in contrast, the published study used 4X Gal sequence with the reporter gene without constitutive promoter in between 4X Gal sequence and the reporter gene [ 21].

The boundary force is determined implicitly without any constitutive relations allowing the present formulation to use larger CFL numbers compared to some past methods.

MCF-7-14 cells are a novel model for breast cancer metastasis without requiring constitutive EMT and are categorized as a "metastable phenotype", which can be distinguished from both epithelial and mesenchymal cells.

Many factors specifically affect AMPAR activity-dependent recycling without affecting constitutive recycling [e.g., AP2 (Lee et al., 2002), Brag2 (Scholz et al., 2010)], and vice versa [e.g., NSF (Lee et al., 2002), PIP3 (Arendt et al., 2010)].

Cell-sheet movement is a typical feature of epithelial cells during embryonic development and wound healing [ 13]; therefore, MCF-7-14 cells may be a novel model for breast cancer metastasis without requiring constitutive EMT.

Lack of this control mechanism in β cells resulted in premature scission, generation of dysfunctional insulin granules and impaired regulated insulin secretion without affecting constitutive release of other transport carriers.