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As activation of a meiotic checkpoint is linked to defects in eggshell patterning (Morris and Lehmann 1999), these findings suggest that oogenesis in Top2 -complementing females occurs without checkpoint activation.
Limiting RNAi doses from 17%to8%8% led to a less severe reduction of GFP-MCM-3 loading without checkpoint activation and without strong chromosome-condensation defects but with occasional anaphase bridges.
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Rivers keep you from driving farther into Canada, but Mr. Day said that in winter, you can cross by snowmobile, and head toward Montreal "without checkpoints".
The Palestinians are alone and, with the exception of extremists among them, there is nothing they would like better than to have peace with Israel, have jobs, send their children to school, have easy access to hospitals, and have the ability to move around without checkpoints, walls and fear of eviction or house demolition.
In an era of suicide bombers, places without checkpoints seem almost naked, like windowless buildings or unfenced playgrounds".
Without this checkpoint, cells formed DSBs on partially replicated chromosomes.
Similarly, Trichostatin A has been shown to induce a delay at the G2/M transition, chromosome missegregation and multi-nucleation, and thereby it leads to cell death by promoting exit from aberrant mitosis without spindle checkpoint.
But you still won't comprehend the Wall without a visit to Checkpoint Charlie.
In order to smuggle the stolen bottles out of the airport, truck drivers gave some of them to three airport security guards, who were also arrested, to let trucks pass through checkpoint areas without being carefully inspected, the authorities said.
Our finding that the very C-terminal Mad1 head is required for checkpoint activity without being required for any of the known Mad1 functions provides a basis to elucidate the molecular mechanism.
Even on regular roads, it's difficult to go through without seeing checkpoints".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com