Sentence examples for without causing systemic from inspiring English sources

Here, we make use of the genetic tools provided by the mouse system to investigate the mechanism by which CD28SA expand Treg cells in the rodent immune system without causing systemic cytokine release, and to ask whether pharmacological suppression of cytokine release would interfere with CD28SA-mediated Treg activation.

"It must be possible that banks fail without causing systemic risks to the financial system," they wrote.

While other countries have defaulted on their sovereign debt in recent times without causing systemic contagion, analysts weighing the numbers on Greece note that its debt is far higher, so the ripple effects could be more serious.

The IMF also recommends that resolution regimes, or "living wills", be mandated alongside this scheme to try to address some of this moral hazard so that taxpayers will not be forced to bail out banks if they can fail without causing systemic collapse.

It can reach very high concentration when delivered locally without causing systemic toxic effects [9, 10].

We conclude that this SN38-TS NP formulation improved delivery, retention, and efficacy, without causing systemic toxicity.

However, the H7N7 viruses are not considered to cause a systemic disease in horses, but they have been described as causing systemic infection in mice without prior adaptation (29 ).

It has therefore been suggested that nonabsorbable agents or agonists with very low systemic exposure might be capable of activating L-cells without causing toxic systemic levels (14), although this approach depends on a better understanding of how bile acids and GPBAR1 ligands access their receptors.

Would this failure cause systemic damage to the financial system?

Our study demonstrates that (I) nitroglycerin but not acetylcholine applied topically to the sublingual mucosa increases both total vessel density and local capillary flow velocity in healthy volunteers, (II) without causing measurable systemic effects.

Leverage, not high prices, causes systemic risks.