To the best of our knowledge there are very limited data in the literature concerning epidemiological studies, where a geographically well-defined population is monitored over time without the application of any large scale intervention.
The LISW induced lung injury model seems to be useful as severe BLI in small animals without any large scaled equipment.
And by untested, we mean that very few animal studies have been produced, its overdose limits are largely speculative, and it comes entirely without any large-scale human studies.
And Gov. George E. Pataki, having proposed a budget without any large-scale tax increases, has not budged, still saying that taxes smother the economy and kill jobs.
The most recent recession, for example, passed without any large-scale bank failures, in contrast to earlier downturns that typically brought banking crises and collapses of financial firms.
The entire detection process could be shortened to 120 min without any large-scale instrumentation.
The model also explains how and why a high heterogeneity of 3D grid cells is expected - from cells exhibiting only triplets of activity-blobs angled at 60-degrees (but without any large-scale lattice organization), through random mixtures of HCP and FCC lattices, and ending with perfectly crystallized HCP and FCC lattices.
However, better estimates are unlikely to be available without a large scale prospective study because of the typically insidious onset of COPD.
Has any large-scale society succeeded without prosocial religion?
It also delivered weapons and ammunition on a large scale – without any clear legal basis.
By contrast, the annual O. nivara wild rices could have been exploited on a large scale without any serious cultivation, or selection of habit changes or domestication traits.
