Sentence examples for without any efficacy from inspiring English sources

Currently available drugs against Alzheimer's disease (AD) are only able to ameliorate the disease symptoms resulting in a moderate improvement in memory and cognitive function without any efficacy in preventing and inhibiting the progression of the pathology.

Most tourists reported using topical insect repellents without any efficacy.

A recent randomised phase II study comparing sunitinib v.s. bevacizumab and interferon v.s bevacizumab and temsirolimus demonstrated significant toxicity for the latter combination without any efficacy advantage (Escudier et al, 2010).

Moreover, combination chemotherapy has proven equally disappointing, because additional drugs have resulted in increased toxicity without any increased efficacy compared with single agent doxorubicin therapy (Whang-Peng and Chao, 1998).

Even without any HSV-efficacy, the relative reduction in HIV incidence is still projected to be 12.0% after 15 years for the main intervention scenario compared to 12.5% if the gel is 71% HSV-2-efficacious.

In theory, the combination of Zetia and a low dose of a drug like Zocor would be safer than a higher dose without any sacrifice in efficacy.

An accompanying viewpoint raises the question: "how could a medical device be so well accepted without any evidence of efficacy?" Researchers conducted a retrospective observational study that compared the frequency of VCF use in 236 California hospitals by analyzing data from 130,643 acute VTE hospitalizations over four years.

They also estimated that infusions greater than 0.04 U/min were accompanied by deleterious effects, without any gain in efficacy.

The main argument for a shorter application time in hand disinfection without any reduction of efficacy is certainly that it is easier to comply with [ 32].

Currently, it has been reported that subcutaneous (SC) administration of bortezomib decreases the incidence of BiPN as compared to standard intravenous (IV) bolus injection without any differences in efficacy.

Dried pre-coated plates could be either used directly for knockdown experiments or be stored for up to 15 months without any loss of efficacy, thus ensuring improved reproducibility and comparability between different plates of the same batch as compared to liquid transfection of siRNA.