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At the same time, Sheldon had also bought the site of 170 East 78th, directly across the street, without any apparent involvement by Taylor.
Second, YAP is negatively regulated in keratinocytes without any apparent involvement of MST1/2 or LATS1/2 signalling [ 115].
Third, in mouse thymocytes MST1/2 mainly signals through phosphorylation of MOB1A/B without any apparent involvement of LATS1/2 or YAP [ 66].
Importantly, we showed that ATR is imperative for the regulation of DSB repair in hESCs without any apparent involvement of ATM.
First, liver specific deletion of MST1/2 in mice causes hepatocellular carcinoma (HCC) by YAP deregulation without any apparent involvement of LATS1/2 [ 6].
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Furthermore, we observe that CpG methylation adds an extra level of repression to Pc-G repression without the apparent involvement of H3K9 methylation.
In other cancer models HER3 is known to be activated without apparent involvement of the other HER family members and may be transactivated by cellular stress and cytokines, including tumour necrosis factor α and interferon α [11].
This point is important, since Zhou et al. showed that MST1/2 signalling plays a crucial role in YAP regulation in colon stem cells without apparent involvement of LATS1/2 signalling [ 122], suggesting that the regulation of YAP in stem cells might not always depend on LATS1/2.
Sometimes, though, it occurs without any apparent underlying cause.
They ate heartily and merrily, without any apparent discernment.
In many instances pyelonephritis develops without any apparent precipitating cause.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com