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Being on first-line therapy included all mutual drug substitutions and combinations within this regimen category.
Furthermore, the cost of first line treatment rises over time (2-4% per month) because of changes in antiretroviral drugs within this regimen.
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The majority of patients administering insulin detemir twice daily (n = 103) were transferred to this regimen within 12 weeks of treatment.
The results, especially in patients with stage III disease, are encouraging and support the investigation of this regimen within a prospective randomised trial.
An optional second randomisation comparing standard 3-weekly therapy with accelerated 2-weekly therapy with GCSF support aimed to test the acceptability and tolerability of this regimen within this patient group.
Using this approach, we were able to increase the dose of oxaliplatin to 100 mg m−2 in an attempt to increase the efficacy of this regimen within the limits of tolerability.
To be eligible patients must also have received the irinotecan-based chemotherapy regimen for at least 6 weeks and must have presented progression of disease during receipt of this regimen or within three months thereafter.
To be eligible, patients must also have received an irinotecan-based chemotherapy regimen for at least 6 weeks and must have presented progression of disease during receipt of this regimen or within 3 months thereafter.
As for how much longer he can continue this regimen, that is not within a mortal's forecast.
An overall regimen adherence rate was calculated at each week as the proportion of doses actually taken relative to the number of doses prescribed summed across each medication within the regimen.
But the research also opened our eyes to the bigger story within which this weekly regimen was nested: living with this disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com