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The lumen is established within these vessels when the small endothelial channels merge into larger channels [14].
Efforts to develop functional tissue-engineered blood vessels have focused on improving the strength and mechanical properties of the vessel wall, while the functional status of the endothelium within these vessels has received less attention.
As blood flow increases, the MTT of the blood flowing within these vessels decreases.
Since a large proportion of total blood volume is contained within these vessels, even small changes in the tone of these 'capacitance' veins will influence cardiac pre-load.
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The presence of amyloid within the walls of these vessels leads to a propensity for primary intracerebral haemorrhage.
The few existing clinical studies, using direct measurements of diameter changes of the radial and temporal arteries, have failed to demonstrate the appearance of nitrate tolerance in these vessels within a study period of 7 [25] and 24 48 h of continuous GTN-infusion [26, 27].
Similar to the invertebrate blood vessels, laminin-containing ECM lines these vessels within the tumor [34].
However, our results demonstrate that reducing the supply of VEGF can still affect these vessels within the first postnatal week of retinal vasculature development.
To rule out an intrinsic loss in immunoreactivity within the neointima of these vessels as an explanation for the loss in AKAP12 and CNN1 expression, adjacent sections were analyzed for macrophage content using the Ham56 antibody (Figure 7C, 7F).
However, the exact location of these vessels within the tissue is not entirely clear.
Therefore, it is particularly important to define the topography of these vessels within the rectal perirectal area.
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