Sentence examples for within the regulatory sequence from inspiring English sources
The initial progression of the systemic inflammatory response can have different manifestations, depending on the specific characteristics of the injury [15]; individual genetics [16], wherein a gene polymorphism within the regulatory sequence affects the levels of cytokine production [10], [17]; and the robustness of the response to tissue damage and ischemia [18].
This allows binding sites to relocate within the regulatory sequence, making it difficult for alignment algorithms to correctly align them.
The presence of methylated cytosines within the nuclear genome of mammals has been extensively investigated and validated in the last 20 years by several lines of evidences, particularly in relation to their role in the gene expression silencing that explains the inverse correlation between density of methylation within the regulatory sequences of a gene and its transcriptional levels.
The regulatory sequences contained within transposable elements are not always optimal, but they can be fine-tuned through evolution.
From the examples described above, it is apparent that the optimal strategy with which to study a lncRNA's loss of function depends both on the mechanism by which it acts, in particular in a cis or trans configuration, and the regulatory sequences present within its locus.
The default region of −500 bp already covers the area in which most of the regulatory sequences are found within the upstream region of A. thaliana genes.
MEME was also used to find conserved motifs in the regulatory sequences of genes within the CUC clade from P. abies and A. thaliana.
In an effort to validate further the microarray gene hits and differentiate between direct and indirect COUP-TFI targets, we set out to identify if COUP-TF response elements were present within the nearby regulatory sequences of the microarray gene hits.
Computational analysis of GST5A found a disproportionate number of DRE cores within the regulatory region sequence of each species.
Despite the well documented involvement of PPARγ in regulating hres expression in human macrophages, paradoxically PPARγ binding site has not been found within the hres regulatory sequences.
The E1A-associated cellular p300 is a positive E-cadherin regulator protein and functions by binding to the two p300 binding sites located within the E-cadherin regulatory sequence [ 63].
