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The randomly chosen reference population had the lowest average relationship within the reference population.
Average (genomic) EBV reliabilities increased with heritability and with a decrease in the average relationship within the reference population.
Four differently designed (i.e., different average relationships within the reference population) small reference populations and 3 heritability levels were considered.
The objective of this study was to investigate the effect of various relationship levels within the reference population and different level of relationship of evaluated animals to the reference population on the reliability of direct genomic breeding values (DGV).
Average reliabilities increased when average relationship within the reference population decreased and the highest average reliabilities were achieved for RND (e.g., from 0.53 in HR to 0.61 in RND for a heritability of 0.30).
Cross-validation within the reference population was used to select the optimum PCR model that minimizes mean squared error.
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Within the training stage, the reference population is divided as training and validation set to conduct cross validation (CV), hence 'folds' and 'replicates' were used in this stage.
The mean IGF-1 at baseline corresponded to a mean IGF-1 SD score within the normal range of the reference population.
Substitutive therapy was changed to 50 75 μg every other day, and both serum TSH and free T4 returned within the corresponding ranges of the reference population.
Clearly, the corresponding PSH in Table 4 did not increase as the reference population was changed from a within-breed to a combined population.
For purebred animals, a reference population of within-breed animals ensures a good performance of imputation, especially when the size of the reference population is large.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com