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As shown in Figures 4A and B, the vast majority (ca. 80%) of CD4+ and CD8+ T cells that produced the effector cytokines IFNγ and TNFα are within the proliferating (CFSElow) population.
Within the proliferating CFSE-low CD8+ T cell subset stimulated with HIV RNA-loaded DC, 24.7% of cells exhibited a phenotype consistent with fully differentiated effector cells (CD8+CD28−CD45RA+) versus 54.8% of cells had a phenotype indicative of effector/memory cells (CD8+CD28+CD45RA−) (Figure 4 Panel B).
Vascular/chondroclast presence within the proliferating (palisading) zone was not seen.
RELM- β was first located within the proliferating cells of the colonic epithelium and disappears as soon as the cell becomes mature.
PAC1 gene transcripts are also present in the EGL [ 26], suggesting that the PACAP and HH pathways might interact within the proliferating cells in this layer.
Inflammatory infiltrates were observed within the proliferating and thickened synovial lining layer with profound lymphocytic and granulocyte infiltration as well as the presence of small vessels (L. Kenner, unpublished data).
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We were particularly interested in any differences which might exist in the expression within and outside the proliferating centers (PCs), as well as in any correlation with patients' clinicopathological and biological characteristics.
Osteogenically differentiated adipose-derived stem cells and/or tendon-derived cells were encapsulated within the hydrogel, proliferating and expressing bone- and tendon-related markers.
Thus, it is intriguing to speculate that DSRCT-specific expression of ENT4, a pH-dependent (acidic) adenosine transporter, might provide growth and survival advantages to the tumor cells (e.g. by stimulating angiogenesis) under hypoxic/acidic conditions, as well as increasing the nucleoside pool within the rapidly proliferating tumor cells.
In the axonal compartment of the DRG, along the dorsal root, and within the DREZ, proliferating cells exhibited a more elongated appearance, resembling nuclei of Schwann cells.
In these hyperplastic jejunal crypts the absolute size of the proliferative compartment was increased, but the growth fraction calculated from labelling studies appeared to fall, probably by reduction in relative size of the proliferating population within the proliferative compartment.
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CEO of Professional Science Editing for Scientists @ prosciediting.com