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Mr. Musonza ordinarily considers himself nothing more than a flyspeck within the hinges of power, but Saturday was election day here, the people's day, his day.
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This comparison allows new insight into the microflow fields within the hinge region of the CarboMedics bileaflet mechanical valve, which have not been previously assessed during its clinical history.
We treated trastuzumab with IdeS and, as expected, IdeS efficiently cleaved trastuzumab within the hinge.
There are eight direct control muscles and three indirect control muscles attached to the various elements within the hinge.
The three other slc alleles of cut14 (slc90, slc90, and slc180) all affect conserved residues located within the hinge domain.
IgG antibody is known to be susceptible to specific cleavage within the hinge region by proteinases in vitro [ 12, 13].
This is a problem since the most highly conserved motif in TorD family proteins (EPxDH) is located within the hinge.
To test this possibility, we constructed CFP and YFP insertions within the hinge in the two Smc1 copies of a diploid strain.
Pattern a has just one intron in phase 0 (P0) within the hinge region at the −5 position, which inserts between the amino acids Gln and Ala.
The functional importance of mutations within the hinge region is less clear, although they could potentially alter the three-dimensional relation between transactivation and DNA-binding domains.
Interestingly, modifications were not random, but instead limited to only few lysines within the hinge area and the N-terminal fragment of the CH2 domain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com